
MIHUE JANG Senior Researcher
– Ph.D. Postech, Life Science (2013)
– B.S. Kyungpook National University , Genetic engineering/ Plant life science (2006)
– Senior Research Scientist, KIST (2015~)
– Postdoctoral Fellow, KIST (2013- 2015)
– Visiting Scholar, Max Planck Institutes, Prof. Paul Schulze-Lefrt,Germany, 2009, 2010-2011)
– Cancer and immune cells-based re-programming using CRISPR/Cas9 for immunotherapy.
– Development of CRISPR/Cas9- delivery platfrom for immunotherapy
– Development of cell reprogramming
– Development of enhanced CAR-NK-mediated cytolysis
– Ultra-high throughput screening system for detection of immunogenicity in patient-derived PBMCs.
1. Seung Min Kim, Sang Chul Shin, Eunice EunKyeong Kim, Sang-Heon Kim, Kwideok Park, Seung Ja Oh*,Mihue Jang*, Simple in Vivo Gene Editing via Direct Self-Assembly of Cas9 Ribonucleoprotein Complexes for Cancer Treatment. ACS NANO, 2018, * Corresponding author
2. Minkoo Seo, Jin-Chul Kim, Hyung-Ki Kim, Eun wook Choi, Suyeong Jeong, Ki Chang Nam*, Mihue Jang*, A Novel Secretory Vesicle from Deer Antlerogenic Mesenchymal Stem Cell-Conditioned Media (DaMSC-CM)Promotes Tissue Regeneration. Stem Cells International, 2018, 3891404, * Corresponding author
3. Minkoo Seo, Seung Min Kim, Eun Young Woo, Ki-Cheol Han, Eun Joo Park, Seongyeol Ko, Eun wook Choi*, Mihue Jang*, Stemness-Attenuating miR-503-3p as a Paracrine Factor to Regulate Growth of Cancer Stem Cells. Stem Cells International, 2018, 4851949, * Corresponding author
4. Seung Min Kim, Yoosoo Yang, Seung Ja Oh, Yeonsun Hong, Minkoo Seo, Mihue Jang*, Cancer-derived exosomes as a delivery platform of CRISPR/Cas9 confer cancer cell tropism-dependent targeting. Journal of Controlled Release, 2017, 266, 8-16. * Corresponding author
5. Seung Min Kim, Yoosoo Yang, Seung Ja Oh, Yeonsun Hong, Minkoo Seo, Mihue Jang*, Cancer-derived exosomes as a delivery platform of CRISPR/Cas9 confer cancer cell tropism-dependent targeting. Journal of Controlled Release, 2017, 266, 8-16. * Corresponding author