의약소재연구센터

양유수 책임연구원

전화번호

02-958-6655

이메일

ysyang@kist.re.kr

위치

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홈페이지

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학력

2012  성균관대학교, 생명공학, 박사

2009  성균관대학교, 생명공학, 석사

2007  성균관대학교, 생명공학, 학사

경력

2021- 한국과학기술연구원, 의약소재연구센터 책임연구원

2014-2021 한국과학기술연구원, 테라그노시스연구센터 선임연구원

2015- UST KIST스쿨, Bio-Med 융합전공, 부교수

2013 Iowa State University, 방문연구원

2012-2014 한국과학기술연구원, 박사후연구원

주요 연구분야

바이오로직스의 체내 전달을 위한 생체 적합 소재 개발

대표성과

– 논문

  1. Eun Hye Kim, Jongwon Lee, Gijung Kwak, Hochung Jang, Hyosuk Kim, Haeun Cho, Yeongji Jang, Jiwoong Choi, Sung-Gil Chi, Kwangmeyung Kim, Ick Chan Kwon, Yoosoo Yang* and Sun Hwa Kim* (2022) “PDL1-binding peptide/Anti-miRNA21 conjugate as a therapeutic modality for PD-L1high tumors and TAMs” J Control Release 345:62-74
  2. Hyosuk Kim, Da Eun Kim, Geonhee Han, Nu Ri Lim, Eun Hye Kim, Yeongji Jang, Haeun Cho, Hochung Jang, Ki Hun Kim, Sun Hwa Kim, Yoosoo Yang* (2021) “Harnessing the Natural Healing Power of Colostrum: Bovine Milk-derived Extracellular Vesicles from Colostrum Facilitating the Transition from Inflammation to Tissue Regeneration for Accelerating Cutaneous Wound Healing” Adv Healthc Mater 5;e2102027
  3. Gi Beom Kim, Gi-Hoon Nam, Yeonsun Hong, Jiwan Woo, Yakdol Cho, Ick Chan Kwon, Yoosoo Yang*, In-San Kim (2020) “Xenogenization of tumor cells by fusogenic exosomes in tumor microenvironment ignites and propagates antitumor immunity” Sci Adv 6(27) eaaz2083
  4. Yoosoo Yang1,*, Gi-Hoon Nam, Gi Beom Kim, Yoon Kyoung Kim, In-San Kim* (2019) “Intrinsic cancer vaccination” Adv Drug Deliv Rev 151-152:2-22
  5. Yoosoo Yang1,*, Yeonsun Hong, Eunji Cho, Gi Beom Kim, and In-San Kim* (2018) “Extracellular vesicles as a platform for membrane-associated therapeutic protein delivery” J Extracell Vesicles, 7(1);144031
  6. Sung Duk Jo, Gi-Hoon Nam, Gijung Kwak, Yoosoo Yang*, Ick Chan Kwon*, (2017) “Harnessing designed nanoparticles: Current strategies and future perspectives in cancer immunotherapy” Nano Today, 17(2017):23-37
  7. Yoosoo Yang1,*, Yeonsun Hong, Gi-Hoon Nam, Jin Hwa Chung, Eunee Koh, and In-San Kim# (2017) “Virus-Mimetic Fusogenic Exosomes for Direct Delivery of Integral Membrane Proteins to Target Cell Membranes” Adv Mater, 29(13)

– 특허

  1. 암 치료용 신규 재조합 원형질막 기반 소포체, 10-2215475 (대한민국, 2021.02.05.)
  2. 하이알유로니데이즈 포함 신규 재조합 엑소좀 및 그의 용도, 10-1964124 (대한민국, 2019.03.06.)
  3. 신규 엑소좀 계열 항암제, 10-2129067 (대한민국, 2020.06.25.) / 6857736 (일본, 2021.03.24.) / 110248645 (중국, 2022.04.26.)
  4. 신규 재조합 엑소좀 및 그의 용도, 10-2052204 (대한민국, 2019.11.28.), 6620129 (일본, 2019.11.22.)
  5. 엑소좀 기반의 직접 교차분화 방법, 10-2213890 (대한민국, 2021.02.02.)